USAG1 (uterine sensitization‑associated gene 1), also called WISE (Wnt modulator in surface ectoderm) or Ectodin, gene name SOSTDC1, is a secreted, monomeric 26 ‑ 32 kDa glycoprotein of the sclerostin family of BMP antagonists. USAG1 is proposed to coordinate BMP, Wnt, FGF and SHH signals that regulate apoptosis during tooth development. Deletion of USAG1 results in mice with supernumerary teeth, while concurrent decreased expression of LRP5 and LRP6 restores normal tooth configurations. USAG1 expression by uterine luminal epithelium is also associated with the timing and positioning of blastocyst implantation.

高活性、高纯度、低内毒素、高批间一致性

-25 ~ -15℃保存，收到货之后有效期1年。复溶后， 2 ~ 8 °C保存，7 天有效期。复溶后， -85 ~ -65℃保存，3个月有效期。建议首次使用时将蛋白等分，避免重复冻融循环。