分子生物学
IVD分子诊断
细胞培养与分析
蛋白研究
细胞因子
重组蛋白
抗体
高通量测序建库
病原检测UCF系列
生物医药
工具酶
抑制剂激活剂与常用试剂
仪器
耗材

Manipulation of genetic recombination by editing the transcriptional regulatory regions of a meiotic gene in hybrid rice

Xin Wei, Qing Liu, Tingting Sun, Xiaozhen Jiao, Chaolei Liu, Yufeng Hua, Xi Chen, Kejian Wang

Journal:Plant Communications

IF:10.5

DOI:10.1016/j.xplc.2022.100474

PMID:

Published:2023-03-13

research field:分子生物学药理学细胞生物学皮肤科免疫学结构生物学生物化学

Abstract

Genetic breeding involves the recombination and selection of various valuable genes. Meiotic crossover (CO) promotes the generation of new allelic combinations on chromosomes, which is essential for breeding elite varieties (Wijnker and de Jong, 2008). An increase in CO promotes genetic diversity, whereas a decrease can rapidly stabilize excellent traits (Mercier et al., 2015). Furthermore, the complete elimination of CO facilitates heterotic fixation during apomixis (Wang et al., 2019). However, the number and distribution of COs are tightly restrained in crops, severely hindering agricultural breeding (Crismani et al., 2012). To date, many meiotic genes involved in CO formation have been identified in different organisms. Unfortunately, null mutations in these genes usually cause infertility, thus preventing direct use of the mutants in crop breeding.

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