Sodium aescinate是一种从Aesculus hippocastanum种子中提取的三萜皂苷,具有抗炎与抗氧化作用。它可通过靶向CARMA3/NF-κB途径抑制肝癌生长。
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英文别名 (English Synonym) |
Sodium Aescinate |
|
中文名称 (Chinese Name) |
七叶皂苷钠 |
|
靶点 (Target) |
Others |
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通路 (Pathway) |
Natural Products |
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CAS号 (CAS NO.) |
20977-05-3 |
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分子式 (Formula) |
C54H83NaO23 |
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分子量 (Molecular Weight) |
1123.21 |
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纯度 (Purity) |
|
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溶解性 (Solubility) |
溶于DMSO |
-25~-15℃保存，有效期3年
[1] Qi SM, Lv J, Meng Y, Qi ZL, Ling LF. [Effect of sodium aescinate in inducing human breast cancer MCF-7 cells apoptosis by inhibiting AKT, ERK and upstream signal SRC activity]. Zhongguo Zhong Yao Za Zhi. 2015 Aug,40(16):3267-72. Chinese. PMID: 26790305.[2]Zhang Z, Cao G, Sha L, Wang D, Liu M. The Efficacy of Sodium Aescinate on Cutaneous Wound Healing in Diabetic Rats. Inflammation. 2015 Oct,38(5):1942-8. doi: 10.1007/s10753-015-0174-5. PMID: 25903967.
