Nedaplatin
产品介绍
Nedaplatin是一种顺铂衍生物，通过引起DNA损伤抑制肿瘤克隆形成。需注意该铂类药物不宜用DMSO溶解，以免失活。
产品性质
产品特色
| 英文别名 (English Synonym) | Nedaplatin |
| 中文名称 (Chinese Name) | |
| 靶点 (Target) | Adrenergic Receptor |
| 通路 (Pathway) | GPCR/G protein |
| CAS号 (CAS NO.) | 95734-82-0 |
| 分子式 (Formula) | C2H8N2O3Pt |
| 分子量 (Molecular Weight) | 303.17 |
| 纯度 (Purity) | ≥98% |
| 溶解性 (Solubility) | 溶于H2O |
存储条件
-25~-15℃保存，有效期3年
COA
已发表文献
[1] Kanzawa F, Koizumi F, Koh Y, Nakamura T, Tatsumi Y, Fukumoto H, Saijo N, Yoshioka T, Nishio K. In vitro synergistic interactions between the cisplatin analogue nedaplatin and the DNA topoisomerase I inhibitor irinotecan and the mechanism of this interaction. Clin Cancer Res. 2001 Jan;7(1):202-9. PMID: 11205910.[2]Uchida N, Takeda Y, Hojo K, Maekawa R, Sugita K, Yoshioka T. Sequence-dependent antitumour efficacy of combination chemotherapy of nedaplatin, a novel platinum complex, with 5-fluorouracil in an in vivo murine tumour model. Eur J Cancer. 1998 Oct;34(11):1796-801. doi: 10.1016/s0959-8049(98)00194-4. PMID: 9893671.
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