Auranofin是一种硫氧还蛋白还原酶抑制剂，具有抗SARS-CoV-2病毒活性及抗癌作用，作为FDA批准的含金化合物用于类风湿关节炎治疗。
| 英文别名 (English Synonym) | Auranofin |
| 中文名称 (Chinese Name) | 醋硫葡金 |
| 靶点 (Target) | Reductases |
| 通路 (Pathway) | Others |
| CAS号 (CAS NO.) | 34031-32-8 |
| 分子式 (Formula) | C20H34AuO9PS |
| 分子量 (Molecular Weight) | 678.48 |
| 纯度 (Purity) | ≥98% |
| 溶解性 (Solubility) | 溶于DMSO |
-25~-15℃保存，有效期3年
[1] Park SH, Lee JH, Berek JS, Hu MC. Auranofin displays anticancer activity against ovarian cancer cells through FOXO3 activation independent of p53. Int J Oncol. 2014 Oct;45(4):1691-8. doi: 10.3892/ijo.2014.2579. Epub 2014 Aug 4. PMID: 25096914; PMCID: PMC4151813.[2]Park N, Chun YJ. Auranofin promotes mitochondrial apoptosis by inducing annexin A5 expression and translocation in human prostate cancer cells. J Toxicol Environ Health A. 2014;77(22-24):1467-76. doi: 10.1080/15287394.2014.955834. PMID: 25343295.[3]Lee JC, Dimartino MJ, Votta BJ, Hanna N. Effect of auranofin treatment on aberrant splenic interleukin production in adjuvant arthritic rats. J Immunol. 1987 Nov 15;139(10):3268-74. PMID: 3500212.
