vitexin-2″-o-rhamnoside是一种口服活性黄酮苷,可通过提高PI3K/Akt磷酸化水平、抑制caspase-3与SOD活性、促进细胞因子(IL-2/IL-6/IL-12)分泌来抑制细胞凋亡;该化合物能强效抑制MCF-7细胞DNA合成,并具有免疫增强、促进活性成分吸收及抗氧化功能,适用于心血管疾病与免疫相关疾病的研究。
| 英文别名 (English Synonym) | vitexin-2″-o-rhamnoside |
| 中文名称 (Chinese Name) | 牡荆素鼠李糖苷 |
| 靶点 (Target) | Others |
| 通路 (Pathway) | Natural Products |
| CAS号 (CAS NO.) | 64820-99-1 |
| 分子式 (Formula) | C27H30O14 |
| 分子量 (Molecular Weight) | 578.16 |
| 纯度 (Purity) | ≥98% |
| 溶解性 (Solubility) | 溶于DMSO |
-25~-15℃保存,有效期3年
[1] Wei W, Ying X, Zhang W, Chen Y, Leng A, Jiang C, Liu J. Effects of vitexin-2"-O-rhamnoside and vitexin-4"-O-glucoside on growth and oxidative stress-induced cell apoptosis of human adipose-derived stem cells. J Pharm Pharmacol. 2014 Jul;66(7):988-97. doi: 10.1111/jphp.12225. Epub 2014 Feb 17. PMID: 24533889.
[2] Cai S, Chen Y, Zhang W, Ying X. Comparative study on the excretion of vitexin-4''-O-glucoside in mice after oral and intravenous administration by using HPLC. Biomed Chromatogr. 2013 Nov;27(11):1375-9. doi: 10.1002/bmc.2931. Epub 2013 Jun 13. PMID: 23760836.





