Sodium Picosulfate是一种口服有效的接触性刺激性泻药，通过抑制肠道对水和电解质的吸收并促进其分泌来发挥作用，临床上主要用于结肠镜检查前的肠道准备。
|
英文别名 (English Synonym) |
Sodium Picosulfate |
|
中文名称 (Chinese Name) |
匹克硫酸钠；匹可硫酸钠 |
|
靶点 (Target) |
Others |
|
通路 (Pathway) |
Others |
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CAS号 (CAS NO.) |
10040-45-6 |
|
分子式 (Formula) |
C18H15NO8S2·2Na |
|
分子量 (Molecular Weight) |
481.41 |
|
纯度 (Purity) |
≥98% |
|
溶解性 (Solubility) |
溶于DMSO |
-25~-15℃保存，有效期3年
[1] Nishikawa J, Kast A. Toxicity study with sodium picosulfate in cultured liver cells of rabbit, rat and man. Arzneimittelforschung. 1981;31(2):321-5. PMID: 7194649. [2] Geboes K, Nijs G, Mengs U, Geboes KP, Van Damme A, de Witte P. Effects of 'contact laxatives' on intestinal and colonic epithelial cell proliferation. Pharmacology. 1993 Oct;47 Suppl 1:187-95. doi: 10.1159/000139858. PMID: 8234428.
