Guaifenesin作为一种从愈创木中提取的祛痰成分，通过增加呼吸道分泌物体积并降低其粘稠度，有效促进痰液排出，从而缓解咳嗽症状。
|
英文别名 (English Synonym) |
Guaifenesin |
|
中文名称 (Chinese Name) |
愈创甘油醚 |
|
靶点 (Target) |
Others |
|
通路 (Pathway) |
Others |
|
CAS号 (CAS NO.) |
93-14-1 |
|
分子式 (Formula) |
C10H14O4 |
|
分子量 (Molecular Weight) |
198.22 |
|
纯度 (Purity) |
≥98% |
|
溶解性 (Solubility) |
溶于DMSO |
-25~-15℃保存，有效期3年
[1] Seagrave J, Albrecht H, Park YS, Rubin B, Solomon G, Kim KC. Effect of guaifenesin on mucin production, rheology, and mucociliary transport in differentiated human airway epithelial cells. Exp Lung Res. 2011 Dec;37(10):606-14. doi: 10.3109/01902148.2011.623116. Epub 2011 Nov 1. PMID: 22044398. [2] Kagan L, Lavy E, Hoffman A. Effect of mode of administration on guaifenesin pharmacokinetics and expectorant action in the rat model. Pulm Pharmacol Ther. 2009 Jun;22(3):260-5. doi: 10.1016/j.pupt.2008.12.020. Epub 2009 Jan 6. PMID: 19166957.
