羟苯丙酯是一种广泛用于化妆品、药品和食品的防腐剂，可由植物和细菌天然产生。研究表明，它通过干扰细胞周期、诱导细胞凋亡和扰乱类固醇生成途径，抑制卵泡发育和类固醇合成功能，并导致大鼠精子数量与活力下降。
|
英文别名 (English Synonym) |
Propylparaben |
|
中文名称 (Chinese Name) |
羟苯丙酯 |
|
靶点 (Target) |
others |
|
通路 (Pathway) |
Others |
|
CAS号 (CAS NO.) |
94-13-3 |
|
分子式 (Formula) |
C10H12O3 |
|
分子量 (Molecular Weight) |
180.2 |
|
纯度 (Purity) |
≥98% |
|
溶解性 (Solubility) |
溶于DMSO |
-25~-15℃保存，有效期3年
[1] Ji X, Xu Z, Criswell HE, Boysen PG. Propyl paraben inhibits voltage-dependent sodium channels and protects cardiomyocytes from ischemia-reperfusion injury. Life Sci. 2004 Apr 30;74(24):3043-52. doi: 10.1016/j.lfs.2003.11.007. PMID: 15051427.[2]Gal A, Gedye K, Craig ZR, Ziv-Gal A. Propylparaben inhibits mouse cultured antral follicle growth, alters steroidogenesis, and upregulates levels of cell-cycle and apoptosis regulators. Reprod Toxicol. 2019 Oct;89:100-106. doi: 10.1016/j.reprotox.2019.07.009. Epub 2019 Jul 12. PMID: 31306770.
