3-羟基苯甲酸是一种具有口服活性的内源性代谢产物。它通过激动GPR81和GPR109A受体，发挥应激反应脱敏作用，在抗炎和镇痛研究中具有应用潜力。
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英文别名 (English Synonym) |
3-Hydroxybenzoic acid |
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中文名称 (Chinese Name) |
间羟基苯甲酸 |
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靶点 (Target) |
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通路 (Pathway) |
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CAS号 (CAS NO.) |
99-06-9 |
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分子式 (Formula) |
C7H6O3 |
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分子量 (Molecular Weight) |
138.12 |
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纯度 (Purity) |
≥98% |
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溶解性 (Solubility) |
溶于DMSO |
-25~-15℃保存，有效期3年
[1] Liu C, Kuei C, Zhu J, Yu J, Zhang L, Shih A, Mirzadegan T, Shelton J, Sutton S, Connelly MA, Lee G, Carruthers N, Wu J, Lovenberg TW. 3,5-Dihydroxybenzoic acid, a specific agonist for hydroxycarboxylic acid 1, inhibits lipolysis in adipocytes. J Pharmacol Exp Ther. 2012 Jun;341(3):794-801. doi: 10.1124/jpet.112.192799. Epub 2012 Mar 20. PMID: 22434674.[2]Khan SA, et al. Potential Anti-Stress, Anxiolytic and Antidepressant Like Activities of Mono-Hydroxybenzoic Acids and Aspirin in Rodents: A Comparative Study. Austin J Pharmacol Ther. 2015;3(3): id1061.
