Alogliptin Benzoate，又称苯甲酸阿格列汀，是可口服的DPP-4抑制剂，IC₅₀为<10 nM，通过促进胰岛素的分泌发挥降糖作用，临床上用于治疗2型糖尿病。

参考文献

[1] Feng J, Zhang Z, Wallace MB, et al. Discovery of alogliptin: a potent, selective, bioavailable, and efficacious inhibitor of dipeptidyl peptidase IV. J Med Chem. 2007 May 17;50(10):2297-300. doi: 10.1021/jm070104l(IF:6.054).

[2] Ta NN, Li Y, Schuyler CA, et al. DPP-4 (CD26) inhibitor alogliptin inhibits TLR4-mediated ERK activation and ERK-dependent MMP-1 expression by U937 histiocytes. Atherosclerosis. 2010 Dec;213(2):429-35. doi: 10.1016/j.atherosclerosis.2010.08.064.

[3] Hao FL, Han XF, Wang XL, et al. The neurovascular protective effect of alogliptin in murine MCAO model and brain endothelial cells. Biomed Pharmacother. 2019 Jan;109:181-187. doi: 10.1016/j.biopha.2018.10.064(IF:3.743).

-25~-15℃保存，有效期3年。