Terazosin hydrochloride dihydrate (Terazosin HCl Dihydrate),又称盐酸特拉唑嗪二水合物,是喹唑啉衍生物,是具有口服活性的α-肾上腺素能受体(α-adrenergic receptor)拮抗剂,具有舒张血管活性,临床上用于治疗高血压和前列腺肥大。
参考文献
[1] Kyprianou N, et, al. Suppression of human prostate cancer cell growth by alpha1-adrenoceptor antagonists doxazosin and terazosin via induction of apoptosis. Cancer Res. 2000 Aug 15;60(16):4550-5.
[2] Ju M, et, al. Efficacy of combination terazosin and nifedipine therapy in postoperative treatment of distal ureteral stones after transurethral ureteroscopic lithotripsy. J Int Med Res. 2020 Apr;48(4):300060520904851.
[3] Vincent J, et al. Pharmacological tolerance to alpha 1-adrenergic receptor antagonism mediated by terazosin in humans. J Clin Invest. 1992 Nov;90(5):1763-8.
冰袋运输。粉末直接保存于-25~-15℃,有效期3年。建议溶解分装后于-25~-15℃干燥保存,避免反复冻融。