U0126-EtOH (U0126 Ethanol)是非ATP竞争性的MEK1/2抑制剂，IC₅₀值为70 nM和60 nM，对其它的MAPKKs没有影响，具有抗病毒活性。U0126最初被鉴定为AP-1转录激活的抑制剂，可抑制含有AP-1反应元件的内源性启动子。

参考文献

[1] Favata MF, et al. Identification of a novel inhibitor of mitogen-activated protein kinase kinase. J Biol Chem. 1998 Jul 17;273(29):18623-32.

[2] Droebner K, et al. Antiviral activity of the MEK-inhibitor U0126 against pandemic H1N1v and highly pathogenic avian influenza virus in vitro and in vivo. Antiviral Res. 2011 Nov;92(2):195-203.

[3] Bessard A, et al. RNAi-mediated ERK2 knockdown inhibits growth of tumor cells in vitro and in vivo. Oncogene. 2008 Sep 11;27(40):5315-25.

冰袋运输。粉末直接保存于-20℃，有效期3年。建议分装后-20℃干燥保存，避免反复冻融。