Interleukin-12 (IL-12), also known as NKSF, TCMF, CLMF and TSF, is a heterodimeric cytokine composed of p35 and p40 subunits. It is produced by monocytes, macrophages, B cells and dendritic cells in response to bacterial lipopolysaccharides and intracellular pathogens. IL-12 signals throughtheIL-12 receptor complex, which is comprised of IL-12 Rβ1 and IL-12 Rβ2. IL-12 induces the proliferation and activation of hematopoietic stem cells, natural killer cells and T- cells. It is indispensible during the development of Th1 cells, leading to the production of IFN-gamma and IL-2.

高纯度、高活性、低内毒素、高批间一致性

-85 ~ -65℃保存，收到货之后有效期1年。复溶后， 2 ~ 8 °C保存，7 天有效期。复溶后， -25 ~ -15℃保存，3个月有效期。建议首次使用时将蛋白等分，避免重复冻融循环。