Epsilon-V1-2
产品介绍
Epsilon-V1-2 (PKCε Inhibitor Peptide, Protein Kinase Cɛ Inhibitor Peptide, ɛV1-2)是一种多肽,PKCε抑制剂,选择性和可逆地抑制PKCβ向细胞内膜转运,显著抑制油酸(OA)诱导的连接蛋白43 (Cx43) Ser368磷酸化,防止OA诱导的心肌细胞缝隙连接解体。
产品性质
产品特色
参考文献
[1]. Yasuzawa, T., et al. The structures of the novel protein kinase C inhibitors K-252a, b, c AND d Journal of Antibiotics 39(8), 1072-1078 (1986).
[2]. Plomp, J.J., et al. Involvement of protein kinases in the upregulation of acetylcholine release at endplates of α-bungarotoxin-treated rats Journal of Physiology 493, 175-186 (1996).
[3]. Zhu, X., et al. Evidence of ectokinase-mediated phosphorylation of osteopontin and bone sialoprotein by osteoblasts during bone formation in vitro Biochemistry Journal 323, 637-643 (1997).
存储条件
冰袋运输。粉末直接保存于-20℃,有效期2年,避免反复冻融。
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