The protein encoded by this gene is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. This subunit serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4.

推荐稀释比 WB: 1/1000-1/5000; FC: 1/200-1/2000

本产品仅用作科学研究！

Flow cytometric analysis of IL13 receptor alpha 1 expression in HepG2 cells using IL13 receptor alpha 1 antibody . Green, isotype control; red, IL13 receptor alpha 1.

Western blotting analysis using IL13 receptor alpha 1 antibody . Total cell lysates (30 μg) from various cell lines were loaded and separated by SDS-PAGE. The blot was incubated with IL13 receptor alpha 1 antibody and HRP-conjugated goat anti-rabbit secondary antibody respectively. Image was developed using FeQ™ ECL Substrate Kit .

Western blotting analysis using IL13 receptor α 1 antibody . IL13 receptor α 1 expression in wild type (WT) and IL13 receptor α 1 shRNA knockdown (KD) HeLa cells with 20 μg of total cell lysates. Hsp90 α serves as a loading control. The blot was incubated with IL13 receptor α 1 antibody and HRP-conjugated goat anti-rabbit secondary antibody respectively. Image was developed using NaQ™ ECL Substrate Kit .

Validation of IL13 receptor alpha 1 knockdown using flow cytometry. Wild-type(WT, Blue) and knockdown(KD, Green) HeLa cells were stained with IL13 receptor alpha 1 antibody and analyzed using BD flow cytometer.

Store at -20℃ for one year.