This gene encodes a high mobility group (HMG) box-containing transcription factor that plays a key role in the Wnt signaling pathway. The protein has been implicated in blood glucose homeostasis. Genetic variants of this gene are associated with increased risk of type 2 diabetes. Several transcript variants encoding multiple different isoforms have been found for this gene.

推荐稀释比 WB: 1/4000-1/20000; FC: 1/200-1/2000; ICC/IF: 1/100-1/1000

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Flow cytometric analysis of Transcription factor 7 like 2 expression in HepG2 cells using Transcription factor 7 like 2 antibody . Green, isotype control; red, Transcription factor 7 like 2.

Immunocytochemical staining of HepG2 cells with Transcription factor 7 like 2 antibody . Nuclei were stained blue with DAPI; Transcription factor 7 like 2 was stained magenta with Alexa Fluor® 647. Images were taken using Leica stellaris 5. Protein abundance based on laser Intensity and smart gain: Medium. Scale bar, 20 μm.

Western blotting analysis using transcription factor 7 like 2 antibody . Total cell lysates (30 μg) from various cell lines were loaded and separated by SDS-PAGE. The blot was incubated with transcription factor 7 like 2 antibody and HRP-conjugated goat anti rabbit secondary antibody respectively. Image was developed using NaQ™ ECL Substrate Kit .

Western blotting analysis using transcription factor 7 like 2 antibody . Transcription factor 7 like 2 expression in wild-type (WT) and transcription factor 7 like 2 (TCF7L2) knockdown (KD) HeLa cells with 20 μg of total cell lysates. Hsp90 α serves as a loading control. The blot was incubated with transcription factor 7 like 2 antibody and HRP-conjugated goat anti-rabbit secondary antibody respectively. Image was developed using NaQ™ ECL Substrate Kit .

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