This gene (IFNGR1) encodes the ligand-binding chain (alpha) of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition, defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection.

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Flow cytometric analysis of Interferon gamma receptor 1 expression in C2C12 cells using Interferon gamma receptor 1 antibody . Green, isotype control; red, Interferon gamma receptor 1.

Immunocytochemical staining of C2C12 cells with Interferon gamma receptor 1 antibody . Nuclei were stained blue with DAPI; Interferon gamma receptor 1 was stained magenta with Alexa Fluor® 647. Images were taken using Leica stellaris 5. Protein abundance based on laser Intensity and smart gain: Medium. Scale bar, 20 μm.

Western blotting analysis using interferon gamma receptor 1 antibody . Total cell lysates (30 μg) from various cell lines were loaded and separated by SDS-PAGE. The blot was incubated with interferon gamma receptor 1 antibody and HRP-conjugated goat anti-rabbit secondary antibody respectively. Image was developed using FeQ™ ECL Substrate Kit .

Western blotting analysis using interferon gamma receptor 1 antibody . Interferon gamma receptor 1 expression in wild-type (WT) and interferon gamma receptor 1 (IFNGR1) shRNA knockdown (KD) 293T cells with 20 μg of total cell lysates. Hsp90 α serves as a loading control. The blot was incubated with interferon gamma receptor 1 antibody and HRP-conjugated goat anti-rabbit secondary antibody respectively. Image was developed using FeQ™ ECL Substrate Kit .

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