The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with epidermal growth factor receptor (EGFR) and ephrin receptors. The protein plays a role in the integrin signaling pathway and cell migration by binding with focal adhesion kinase (FAK). Several transcript variants encoding two different isoforms have been found for this gene.

推荐稀释比 WB: 1/1000-1/5000; FC: 1/200-1/2000

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Flow cytometric analysis of growth factor receptor bound protein 7 expression in HepG2 cells using growth factor receptor bound protein 7 antibody . Green, isotype control; red, growth factor receptor bound protein 7.

Western blotting analysis using growth factor receptor bound protein 7 antibody . Total cell lysates (30 μg) from various cell lines were loaded and separated by SDS-PAGE. The blot was incubated with growth factor receptor bound protein 7 antibody and HRP-conjugated goat anti-rabbit secondary antibody respectively. Image was developed using FeQ™ ECL Substrate Kit .

Western blotting analysis using growth factor receptor bound protein 7 antibody . Growth factor receptor bound protein 7 expression in wild type (WT) and growth factor receptor bound protein 7 (GRB7) shRNA knockdown (KD) HeLa cells with 20 μg of total cell lysates. Hsp90 α serves as a loading control. The blot was incubated with growth factor receptor bound protein 7 antibody and HRP-conjugated goat anti-rabbit secondary antibody respectively. Image was developed using NaQ™ ECL Substrate Kit .

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