This gene encodes a DNA binding protein that specifically binds nuclear matrix attachment regions. The encoded protein is involved in transcription regulation and chromatin remodeling. Defects in this gene are associated with isolated cleft palate and cognitive disability. Alternate splicing results in multiple transcript variants that encode the same protein.

推荐稀释比 WB: 1/1000-1/5000; FC: 1/200-1/2000; IHC-P: 1/100-1/200

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Flow cytometric analysis of SATB2 expression in HeLa cells using SATB2 antibody . Green, isotype control; red, SATB2.

Western blotting analysis using SATB2 antibody . Total cell lysates (30 μg) from various cell lines were loaded and separated by SDS-PAGE. The blot was incubated with SATB2 antibody and HRP-conjugated goat anti-rabbit secondary antibody respectively. Image was developed using FeQ™ ECL Substrate Kit .

Western blotting analysis using SATB2 antibody . SATB2 expression in wild-type (WT) and SATB2 knockout (KO) HeLa cells with 20 μg of total cell lysates. β-Tubulin serves as a loading control. The blot was incubated with SATB2 antibody and HRP-conjugated goat anti-rabbit secondary antibody respectively. Image was developed using NaQ™ ECL Substrate Kit .

Immunohistochemistry was performed on paraffin-embedded human sigmoid colon carcinoma using SATB2 antibody . Antigen retrieval was done in sodium citrate buffer (pH 6.0). DAB was used for detection, with hematoxylin counterstaining. Images were acquired using a Nikon Ci-L Plus microscope (40× objective). Scale bar, 25 μm.

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