Predicted to enable protein serine/threonine kinase activity. Involved in several processes, including early endosome to late endosome transport; phosphatidylinositol 3-kinase/protein kinase B signal transduction; and phosphatidylinositol-3-phosphate biosynthetic process. Located in ciliary basal body; intercellular bridge; and late endosome. Part of phosphatidylinositol 3-kinase complex, class III.

推荐稀释比 WB: 1/1000-1/5000; FC: 1/100-1/1000

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Western blotting analysis using PIK3R4 antibody . Total cell lysates (30 μg) from various cell lines were loaded and separated by SDS-PAGE. The blot was incubated with PIK3R4 antibody and HRP-conjugated goat anti-rabbit secondary antibody respectively. Image was developed using NaQ™ ECL Substrate Kit .

Western blotting analysis using PIK3R4 antibody . PIK3R4 expression in wild-type (WT) and PIK3R4 shRNA knockdown (KD) HeLa cells with 20 μg of total cell lysates. Hsp90 α serves as a loading control. The blot was incubated with PIK3R4 antibody and HRP-conjugated goat anti-rabbit secondary antibody respectively. Image was developed using FeQ™ ECL Substrate Kit .

Flow cytometric analysis of PIK3R4 expression in HepG2 cells using PIK3R4 antibody . Green, isotype control; red, PIK3R4.

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