The protein encoded by this gene is part of the multimeric HBO1 complex, which possesses histone H4-specific acetyltransferase activity. This activity is required for functional replication origins and is involved in transcriptional activation of some genes. In both cases, the acetylation of histone H4 helps unfold chromatin so that the DNA can be accessed and replicated or transcribed.

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Flow cytometric analysis of Lysine acetyltransferase 7 expression in HepG2 cells using Lysine acetyltransferase 7 antibody . Green, isotype control; red, Lysine acetyltransferase 7.

Immunocytochemical staining of HepG2 cells with Lysine acetyltransferase 7 antibody . Nuclei were stained blue with DAPI; Lysine acetyltransferase 7 was stained magenta with Alexa Fluor® 647. Images were taken using Leica stellaris 5. Protein abundance based on laser Intensity and smart gain: Medium. Scale bar, 20 μm.

Western blotting analysis using Lysine acetyltransferase 7 antibody . Total cell lysates (30 μg) from various cell lines were loaded and separated by SDS-PAGE. The blot was incubated with Lysine acetyltransferase 7 antibody and HRP-conjugated goat anti-rabbit secondary antibody respectively. Image was developed using FeQ™ ECL Substrate Kit .

Western blotting analysis using lysine acetyltransferase 7 antibody . Lysine acetyltransferase 7 expression in wild type (WT) and lysine acetyltransferase 7 (KAT7) shRNA knockdown (KD) HeLa cells with 30 μg of total cell lysates. Hsp90 α serves as a loading control. The blot was incubated with lysine acetyltransferase 7 antibody and HRP-conjugated goat anti-rabbit secondary antibody respectively. Image was developed using FeQ™ ECL Substrate Kit .

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