This gene encodes a specific binding protein for a vitamin A family member and is thought to play an important role in retinoic acid-mediated differentiation and proliferation processes. It is structurally similar to the cellular retinol-binding proteins, but binds only retinoic acid at specific sites within the nucleus, which may contribute to vitamin A-directed differentiation in epithelial tissue.

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Western blotting analysis using cellular retinoic acid binding protein 1 antibody . Total cell lysates (30 μg) from various cell lines were loaded and separated by SDS-PAGE. The blot was incubated with cellular retinoic acid binding protein 1 antibody and HRP-conjugated goat anti-rabbit secondary antibody respectively. Image was developed using FeQ™ ECL Substrate Kit .

Western blotting analysis using cellular retinoic acid binding protein 1 antibody . Cellular retinoic acid binding protein 1 expression in wild-type (WT) and cellular retinoic acid binding protein 1 (CRABP1) shRNA knockdown (KD) C2C12 cells with 20 μg of total cell lysates. β-Tubulin serves as a loading control. The blot was incubated with cellular retinoic acid binding protein 1 antibody and HRP-conjugated goat anti-rabbit secondary antibody respectively. Image was developed using NaQ™ ECL Substrate Kit .

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