The protein encoded by this gene is a type I membrane protein and member of the immunoglobulin superfamily. It is thought to be involved in the process of myelination. It is a lectin that binds to sialylated glycoconjugates and mediates certain myelin-neuron cell-cell interactions. Three alternatively spliced transcripts encoding different isoforms have been described for this gene.

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Western blotting analysis using myelin associated glycoprotein antibody . Myelin associated glycoprotein expression in wild type (WT) and myelin associated glycoprotein (MAG) shRNA knockdown (KD) HT-1080 cells with 20 μg of total cell lysates. β-Tubulin serves as a loading control. The blot was incubated with myelin associated glycoprotein antibody and HRP-conjugated goat anti-rabbit secondary antibody respectively. Image was developed using NaQ™ ECL Substrate Kit .

Western blotting analysis using myelin associated glycoprotein antibody . Total cell lysates (30 μg) from various cell lines were loaded and separated by SDS-PAGE. The blot was incubated with myelin associated glycoprotein antibody and HRP-conjugated goat anti-rabbit secondary antibody respectively. Image was developed using NaQ™ ECL Substrate Kit .

Flow cytometric analysis of Myelin associated glycoprotein expression in HeLa cells using Myelin associated glycoprotein antibody . Green, isotype control; red, Myelin associated glycoprotein.

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