This gene encodes a membrane-associated enzyme located at a branch point in the mevalonate pathway. The encoded protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene.

推荐稀释比 WB: 1/2500-1/5000; FC: 1/200-1/2000; ICC/IF: 1/100-1/1000

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Flow cytometric analysis of Farnesyl-diphosphate farnesyltransferase 1 expression in HAP-1 cells using Farnesyl-diphosphate farnesyltransferase 1 antibody . Green, isotype control; red, Farnesyl-diphosphate farnesyltransferase 1.

Immunocytochemical staining of HAP-1 cells with Farnesyl-diphosphate farnesyltransferase 1 antibody . Nuclei were stained blue with DAPI; Farnesyl-diphosphate farnesyltransferase 1 was stained magenta with Alexa Fluor® 647. Images were taken using Leica stellaris 5. Protein abundance based on laser Intensity and smart gain: Medium. Scale bar, 20 μm.

Western blotting analysis using farnesyl-diphosphate farnesyltransferase 1 antibody . Total cell lysates (30 μg) from various cell lines were loaded and separated by SDS-PAGE. The blot was incubated with farnesyl-diphosphate farnesyltransferase 1 antibody and HRP-conjugated goat anti-mouse secondary antibody respectively. Image was developed using NaQ™ ECL Substrate Kit.

Western blotting analysis using farnesyl-diphosphate farnesyltransferase 1 antibody . Farnesyl-diphosphate farnesyltransferase 1 expression in wild type (WT) and farnesyl-diphosphate farnesyltransferase 1 (FDFT1) shRNA knockdown (KD) HT-1080 cells with 20 μg of total cell lysates. Hsp90 α serves as a loading control. The blot was incubated with farnesyl-diphosphate farnesyltransferase 1 antibody and HRP-conjugated goat anti-mouse secondary antibody respectively. Image was developed using NaQ™ ECL Substrate Kit .

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