iRGD peptide是由9个氨基酸组成的环肽，先与αv-integrins结合，经酶解产生CRGDK/R序列后再与神经纤毛蛋白-1（neuropilin-1）相互作用，能促进活性分子的组织渗透，具备肿瘤靶向和肿瘤渗透的作用。

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