Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cellular context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements.

推荐稀释比 WB:1/1000-1/5000; ICC/IF:1/100-1/200; FC:1/200-1/500; IP:1/50-1/100

Immunocytochemistry analysis of ERK1/2 (green) in K562 using ERK1/2 antibody,and DAPI(blue).

Western blot analysis of p42 MAPK (ERK2) in K562, rat Brain, C6, 3T3, Hela lysates using p42 MAPK (ERK2) antibody.

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