This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4.

推荐稀释比 WB:1/500-1/1000; IHC:1/50-1/100; IF:1/50-1/200

Western blot analysis of MCP1 in various cell lines lysates using MCP1 antibody.

Immunohistochemistry analysis of paraffin-embedded Human colon using MCP1 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Immunohistochemistry analysis of paraffin-embedded Human stomach using MCP1 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Immunohistochemistry analysis of paraffin-embedded mouse heart using MCP1 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Immunofluorescence analysis of MCP1 in MCF-7 using MCP1 antibody,and DAPI (blue).

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。