Parkin兔单克隆抗体(Parkin Rabbit mAb) Parkin兔单抗（773021ES）

Parkin is a zinc-finger protein that is related to ubiquitin at the amino terminus. The wild type Parkin gene, which maps to human chromosome 6q25. 2- 27, encodes a 465 amino acid full-length protein that is expressed as multiple isoforms ranging from 50-58 kDa. Mutations in the Parkin gene are responsible for utosomal recessive juvenile Parkinson’s disease and commonly involve deletions of exons 3-5. In humans, Parkin is expressed in a subset of cells of the basal ganglia, midbrain, cerebellum and cerebral cortex, and is subject to alternative splicing in different tissues. Parkin expression is also high in the brainstem of mice, with the majority of immunopositive cells being neurons. The Parkin gene has been identified in a diverse group of organisms including mammals, birds, frog and fruit flies, suggesting that analogous functional roles of the Parkin protein may have been highly conserved during the course of evolution

推荐稀释比 WB:1/1000-1/2000; IHC:1/100-1/200; IF:1/50-1/200; FC:1/50-1/100; IP:1/50

Western blot analysis of Parkin in Jurkat，Mouse brain ，rat Brain lysates using Parkin antibody.

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。