YAP (Yes-associated protein, YAP65) was identified based on its ability to associate with the SH3 domain of Yes. Transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis.

推荐稀释比 WB:1/1000-1/2000; IHC:1/50-1/100

Western blot analysis of Phospho-YAP1 (S127) in (1) HeLa lysates; (2) HeLa lysates treated with FBS+Calyculin A using Phospho-YAP1 (Ser127) antibody.

Immunohistochemistry analysis of paraffin-embedded Human stomach using Phospho-YAP1 (S127) antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

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