Cytokeratin 19 Mouse mAb
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The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. The type I cytokeratins are clustered in a region of chromosome 17q12-q21.

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推荐稀释比 WB:1/500-1/1000; IHC:1/100-1/200; IF:1/50-1/200

应用案例

Western blot analysis of Cytokeratin 19 in T47D (1), MCF-7 (2), HepG2 (3) and SW620 (4) cell lysate using Cytokeratin 19 antibody.

Immunohistochemistry analysis of paraffin-embedded human cervical cancer tissues using Cytokeratin 19 antibody.

Immunocytochemistry analysis of Cytokeratin 19 in HepG2 cells using Cytokeratin 19 antibody (green),and DAPI(blue). Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.

存储条件

-25 ~ -15℃保存,收到货之后有效期1年,避免反复冻融。

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