The activated kinase acts on a variety of targets. Likely to be the GTPase effector that links the Rho-related GTPases to the JNK MAP kinase pathway. Activated by CDC42 and RAC1. Involved in dissolution of stress fibers and reorganization of focal complexes. Involved in regulation of microtubule biogenesis through phosphorylation of TBCB.

推荐稀释比 IHC:1/50-1/100;ICC-1/100-1/200

Immunohistochemistry analysis of paraffin-embedded Human breast carcinoma tissue using Phospho-PAK1/2/3 (Thr423/Thr402/Thr421) antibody.Sample with blocking peptide on the right.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Immunofluorescence analysis of Phospho-PAK1/2/3 (Thr423/Thr402/Thr421) in Hela cells using Phospho-PAK1/2/3 (Thr423/Thr402/Thr421) antibody,and DAPI (blue).

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。