TPRKB is a component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t6A37) in tRNAs. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. TPRKB acts as an allosteric effector that regulates the t6A activity of the complex.

推荐稀释比 WB:1/500-1/1000;ICC/IF:1/50

Western blot analysis of TPRKB in lysates of Caco-2,Raji,A549 and Jurkat using TPRKB antibody.

Immunocytochemistry analysis of TPRKB(green) in PBMCs using TPRKB antibody,and DAPI(blue).

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