Calcium-activated, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase involved in various cellular processes such as regulation of the B-cell receptor (BCR) signalosome, oxidative stress-induced apoptosis, androgen receptor-dependent transcription regulation, insulin signaling and endothelial cells proliferation. Plays a key role in B-cell activation by regulating BCR-induced NF-kappa-B activation. Mediates the activation of the canonical NF-kappa-B pathway (NFKB1) by direct phosphorylation of CARD11/CARMA1 at 'Ser-559', 'Ser-644' and 'Ser-652'.

推荐稀释比 WB:1/500-1/1000;IHC:1/50-1/100;IF:1/50-1/200

Western blot analysis of Phospho-PKC beta 2 (Thr641) in JK untreated or treated with PMA lysates using PKCbeta (Phospho-Thr641) antibody.

Immunofluorescence analysis of Phospho-PKC beta 2 (Thr641) in MCF-7 using PKCb(Phospho-Thr641) antibody.

Immunohistochemistry analysis of paraffin-embedded Human lung carcinoma tissue using PKCb(Phospho-Thr641) antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。