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Phospho-Bad (Ser136) Rabbit pAb
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Promotes cell death. Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2. Appears to act as a link between growth factor receptor signaling and the apoptotic pathways.

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推荐稀释比 WB:1/500-1/1000;IHC:1/50-1/100

应用案例

Western blot analysis of Phospho-Bad (Ser136) in HT-29 lysates untreated or treated with UV using BAD (Phospho-Ser136) antibody.

Immunohistochemistry analysis of paraffin-embedded Human breast carcinoma tissue using BAD (Phospho-Ser136) antibody(left) or the same antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.Sample with blocking peptide on the right.

存储条件

-25 ~ -15℃保存,收到货之后有效期1年,避免反复冻融。

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