Serine/threonine-protein kinase involved in various processes such as p38/MAPK14 stress-activated MAPK cascade, DNA damage response and regulation of cytoskeleton stability. Phosphorylates MAP2K3, MAP2K6 and MARK2. Acts as an activator of the p38/MAPK14 stress-activated MAPK cascade by mediating phosphorylation and subsequent activation of the upstream MAP2K3 and MAP2K6 kinases. Involved in G-protein coupled receptor signaling to p38/MAPK14. In response to DNA damage, involved in the G2/M transition DNA damage checkpoint by activating the p38/MAPK14 stress-activated MAPK cascade, probably by mediating phosphorylation of MAP2K3 and MAP2K6.

推荐稀释比 WB:1/500-1/1000;IHC:1/50-1/100

Western blot analysis of Phospho-TAOK1(Ser181)/TAOK2 (Ser181)/TAOK3 (Ser177) in 3T3 lysates using Phospho-TAOK1/2/3 (Ser181/Ser181/Ser177) antibody.

Western blot analysis of TAOK1 (Phospho-Ser181)/TAOK2 (Phospho-Ser181)/TAOK3 (Phospho-Ser177) in Hela, A549, HL-60, U2OS, C6 lysates using TAOK1 (Phospho-Ser181)/TAOK2 (Phospho-Ser181)/TAOK3 (Phospho-Ser177) antibody.

Immunohistochemistry analysis of paraffin-embedded Human tonsil using TAOK1 (Phospho-Ser181)/TAOK2 (Phospho-Ser181)/TAOK3 (Phospho-Ser177) antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。