Proteasomal ubiquitin receptor ADRM1 is a protein that is encoded by the ADRM1 gene. It is a component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. ADRM1 engages and activates 19S-associated deubiquitinases UCHL5 and PSMD14 during protein degradation.

推荐稀释比 WB:1/500-1/1000;IHC-P:1/50-1/100

Western blot analysis of ADRM1 in lysates of HEK-293 and K-562 using ADRM1 antibody.

Immunohistochemistry analysis of paraffin-embedded Human gastric carcinoma using ADRM1 antibody.High pressure and temperature Tris/EDTA (PH 9.0) used for antigen retrieval.The brown color represents the positive signal observed with ADRM1 antibody.

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