Rsk1 is a member of a family of 90kDa ribosomal protein S6 kinases, which includes Rsk1, Rsk2 and Rsk3. These are broadly expressed serine / threonine protein kinases activated in response to mitogenic stimuli, including extracellular signal regulated protein kinases Erk1 and Erk2. Rsk1 is activated by MAPK in vitro and in vivo via phosphorylation. Active Rsks appear to play a major role in transcriptional regulation by translocating to the nucleus and phosphorylating c-Fos and CREB.

推荐稀释比 WB:1/500-1/1000

Western blot analysis of Phospho-RSK1 p90 (Ser352) in HUVEC lysates using p90RSK (Phospho-Ser352) antibody(Lane 2) and the same antibody preincubated with blocking peptide (Lane1).

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。