This gene encodes a class-1 polypeptide chain release factor. The encoded protein plays an essential role in directing termination of mRNA translation from the termination codons UAA, UAG and UGA. This protein is a component of the SURF complex which promotes degradation of prematurely terminated mRNAs via the mechanism of nonsense-mediated mRNA decay (NMD). Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 6, 7, and X.

推荐稀释比 WB:1/500-1/1000;FC:1/50-1/100;ELISA:1/10000

Western blot analysis of RF1 in MCF-7 (1), T47D (2), MOLT4 (3), and Raji (4) cell lysate using RF1 antibody.

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。