Phosphatase and tensin homolog (PTEN) was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency.I t is one of the most commonly lost tumor suppressors in human cancer. During tumor development, mutations and deletions of PTEN occur that inactivate its enzymatic activity leading to increased cell proliferation and reduced cell death. Frequent genetic inactivation of PTEN occurs in glioblastoma, endometrial cancer,and prostate cancer; and reduced expression is found in many other tumor types such as lung and breast cancer.

推荐稀释比 ELISA:1/1000-1/5000;WB:1/500-1/1000

Western blot analysis of recombinant PTEN R130G) and wild type proteins. Purified His-tagged FGFR1 (R130G) protein (lane 2) and corresponding wild type protein (lane 1) were blotted with anti-PTEN (R130G) monoclonal antibody.

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。