EGFR is a receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. It activates at least 4 major downstream signaling cascades including the RAS-RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. Defects in EGFR are associated with lung cancer (LNCR).

推荐稀释比 ELISA:1/1000-1/5000;WB:1/1000-1/5000;IHC-P:1/50-1/200

Western blot analysis of recombinant EGFR (S768I) and wild type proteins.Purified His-tagged EGFR (S768I) protein (lane 1) and corresponding wild type protein (amino acids 702-987, lane 2) were blotted with anti EGFR(S768I) mouse monoclonal antibody.

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。