This gene encodes a member of the mitogen-activated protein kinase (MAPK) family. Members of this family act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. They form a three-tiered signaling module composed of MAPKKKs, MAPKKs, and MAPKs. This protein is phosphorylated at serine and threonine residues by MAPKKKs and subsequently phosphorylates downstream MAPK targets at threonine and tyrosine residues. A similar protein in mouse has been reported to play a role in liver organogenesis. A pseudogene of this gene is located on the long arm of chromosome X. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

推荐稀释比 WB:1/500-1/1000;IP:1/20

Western blot analysis of Phospho-MEK4/MKK4 (Ser80) in 3T3 lysates using Phospho-MEK4 (Ser80) antibody.

Western blot analysis of Phospho-MEK4/MKK4 (Ser80) in A549, MCF-7, U251 lysates using Phospho-MEK4/MKK4 (Ser80) antibody.

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。