HIP1 plays a role in clathrin-mediated endocytosis and trafficking, which is involved in regulating AMPA receptor trafficking in the central nervous system in an NMDA-dependent manner. It regulates presynaptic nerve terminal activity. It can enhance androgen receptor (AR)-mediated transcription and may act as a proapoptotic protein that induces cell death by acting through the intrinsic apoptosis pathway. It can bind 3-phosphoinositides (via ENTH domain). It is required for differentiation, proliferation, and/or survival of somatic and germline progenitors.

推荐稀释比 WB:1/500-1/1000;ICC/IF:1/50

Western blot analysis of HIP1 in lysates of A549,HCT 116 and Neuro-2a using HIP1 antibody.

Immunocytochemistry analysis of HIP1(green) in Neuro-2a cell line using HIP1 antibody,and DAPI(blue).

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。