Rac and Cdc42 are members of the Rho-GTPase family. In mammals, Rac exists as three isoforms, Rac1, Rac2 and Rac3, which are highly similar in sequence. Rac1 and Cdc42, the most widely studied of this group, are ubiquitously expressed. Rac2 is expressed in cells of hematopoietic origin, and Rac3, while highly expressed in brain, is also found in many other tissues. Rac and Cdc42 play key signaling roles in cytoskeletal reorganization, membrane trafficking, transcriptional regulation, cell growth and development.

推荐稀释比 WB:1/500-1/1000

Western blot analysis of Phospho-Rac1/Cdc42 (Ser71) in (1) A431 lysates treated with LP; (2) A431 lysates using Phospho-Rac1/CDC42 (Ser71) antibody.

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。