Binds CpG islands in promoters where the DNA is methylated at position 5 of cytosine within CpG dinucleotides. Binds hemimethylated DNA as well. Recruits histone deacetylases and DNA methyltransferases.

推荐稀释比 WB:1/500-1/1000;IHC:1/50-1/100;IF:1/50-1/200;IP:1/20

Immunocytochemistry analysis of MBD2 (green) in HL-60 using MBD2 antibody,and DAPI(blue).

Western blot analysis of MBD2 in rat Brain, C6, 3T3, Hela lysates using MBD2 antibody.

Immunohistochemistry analysis of paraffin-embedded Human tonsil using MBD2 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Store at 4°C short term. Aliquot and store at -22°C long term. Avoid freeze/thaw cycles.