The protein encoded by this gene is expressed in B lymphocytes and contains pleckstrin homology and src homology 2 (SH2) domains. In Burkitt's lymphoma cell lines, it is tyrosine-phosphorylated in response to B cell receptor stimulation. Because it binds Shc independent of stimulation and Grb2 after stimulation, it appears to play a role in signal transduction from the receptor to the Shc/Grb2 pathway.

推荐稀释比 IHC:1/100-1/200;FC:1/50-1/100;ELISA:1/10000

Immunohistochemistry analysis of paraffin-embedded human colon cancer tissues using SH2B2 antibody.

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。