The Syk family protein tyrosine kinase Zap-70 is expressed in T and NK cells and plays a critical role in mediating T cell activation in response to T cell receptor (TCR) engagement. Following TCR engagement, Zap-70 is rapidly phosphorylated on several tyrosine residues through autophosphorylation and transphosphorylation by the Src family tyrosine kinase Lck.

推荐稀释比 IHC:1/100-1/200

Immunohistochemistry analysis of paraffin-embedded Tonsil using ZAP70 antibody.High-pressure and temperature Tris-EDTA pH 8.0 was used for antigen retrieval.

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