C9 is synthesised in the liver and monocytes, and is a plasma protein consisting of a single polypeptide chain of molecular weight 71kDa. Normal plasma concentration is 60mg/L. C9 forms part of the membrane attack complex (MAC) the cytolytic terminal complex of the complement pathways. C9 binds to the membrane associated C5b-8, binding of C9 to C5b-8 leads to the circular polymerisation of 12-18 C9 molecules. This is the basis of the hydrophilic, protein-walled, trans-membrane channel formed by the MAC, which leads to cell lysis and destruction.

推荐稀释比 WB:1/500-1/1000;IHC:1/50-1/100;IP:1/50

Western blot analysis of C9 in Human fetal liver lysates using Complement C9 antibody.

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。