The protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein was found to interact with TYROBP/DAP12, a protein bearing immunoreceptor tyrosine-based activation motifs. This protein was also reported to participate in the recruitment of tyrosine kinase SYK. Multiple transcript variants encoding different isoforms have been found for this gene.

推荐稀释比 IHC:1/100-1/200;IF:1/50-1/200;FC:1/50-1/100;ELISA:1/10000

Immunohistochemistry analysis of paraffin-embedded human colon cancer tissues using CD172b antibody.

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。