This gene encodes a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. It regulates the differentiation and development of melanocytes retinal pigment epithelium and is also responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory-pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.

推荐稀释比 WB:1/500-1/1000;FC:1/50-1/100;ELISA:1/10000

Flow Cytometry analysis of Hela cells using MITF antibody (green) and negative control (red).

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。